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Fomepizole and alcohol

Result of checker of drug Fomepizole interaction with alcohol. Whether they can be taken together or this combination is not allowed.

Check result:

Fomepizole <> Alcohol

Relevance: 01.01.2021

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with alcohol.

Consumer:

Ask your doctor before using ethanol together with fomepizole. Ethanol and fomepizole should not be given together in the treatment of ethylene glycol poisoning. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: The manufacturer reports that oral doses of fomepizole (10 to 20 mg/kg) will significantly reduce the rate of elimination of moderate doses of ethanol by approximately 40% when given to healthy volunteers. The mechanism is via alcohol dehydrogenase inhibition. By a similar mechanism, ethanol will decrease the rate of elimination of fomepizole.

MANAGEMENT: In general, ethanol and fomepizole should not be coadministered in the treatment of ethylene glycol poisoning.

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