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Dextromethorphan, phenylephrine, and pyrilamine and alcohol

Result of checker of drug Dextromethorphan, phenylephrine, and pyrilamine interaction with alcohol. Whether they can be taken together or this combination is not allowed.

Check result:
Dextromethorphan, phenylephrine, and pyrilamine <> Alcohol
Relevance: 01.01.2021

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with alcohol.

Consumer:

Consumer information for this interaction is not currently available.

Professional:

GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.

MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

References:
  • Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):
  • Warrington SJ, Ankier SI, Turner P "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology 15 (1986): 31-7
  • "Product Information. Fycompa (perampanel)." Eisai Inc, Teaneck, NJ.
  • "Product Information. Rexulti (brexpiprazole)." Otsuka American Pharmaceuticals Inc, Rockville, MD.
Dextromethorphan, phenylephrine, and pyrilamine

Generic Name: dextromethorphan / phenylephrine / pyrilamine

Brand Name: Codal-DM Syrup, Codimal DM, Codituss DM, Poly Hist DM, Viravan-DM, V-Tan DM, Zotex-12, Deconsal DM Tannate, Aldex DM, Viratan-DM, Triplex DM, MyHist-DM, Tannate V DM, Reme Hist DM, Pryil DM, Pyril DM

Synonyms: Pyril Mal Phenyl HCl Dex HBr