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Abacavir, lamivudine, and zidovudine and alcohol

Result of checker of drug Abacavir, lamivudine, and zidovudine interaction with alcohol. Whether they can be taken together or this combination is not allowed.

Check result:

Abacavir, lamivudine, and zidovudine <> Alcohol

Relevance: 01.01.2021

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug interaction with alcohol.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Consumption of ethanol during treatment with abacavir results in a decrease in elimination of abacavir due to the inhibition of alcohol dehydrogenase. Coadministration of alcohol 0.7 g/kg (equivalent to 5 drinks) and abacavir resulted in a 41% increase in the area under the time concentration curve and a 26% increase in elimination half life. The clinical significance of this interaction is unknown.

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